Registro completo |
Provedor de dados: |
Genet. Mol. Biol.
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País: |
Brazil
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Título: |
Expression of the bacterial recA gene impairs genetic recombination and sporulation in a Saccharomyces cerevisiae diploid strain
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Autores: |
Morais Junior,Marcos Antonio de
Santos,José Ferreira dos
Henriques,João Antonio Pegas
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Data: |
2003-01-01
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Ano: |
2003
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Palavras-chave: |
DNA repair
Genetic recombination
RecA gene
Sporulation
Yeast
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Resumo: |
The Escherichia coli RecA protein (RecAp) has been demonstrated to induce mutagenesis in yeast cells, although there is still little information on the role of the RecAp in yeast recombination events. We evaluated spontaneous and induced general recombination in vegetative and meiotic cells of the XS2316 strain of the yeast Saccharomyces cerevisiae bearing the recA gene. We found that RecAp decreased reciprocal recombination, gene conversion and intrachromosomal recombination and promoted an increase in error-prone processes in both vegetative and meiotic cells, while its negative effect on meiotic recombination blocked ascospore formation.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000200016
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Editor: |
Sociedade Brasileira de Genética
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Relação: |
10.1590/S1415-47572003000200016
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Formato: |
text/html
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Fonte: |
Genetics and Molecular Biology v.26 n.2 2003
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Direitos: |
info:eu-repo/semantics/openAccess
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